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Dr. Jean Gariepy

PRINCIPAL INVESTIGATOR

Dr. Jean Gariépy was originally trained as a peptide chemist and biophysicist at the University of Alberta (Ph.D.), and as a peptide/protein engineer at Stanford University, in the areas of bacterial toxins and infectious diseases (as a postdoctoral fellow). He is the Director of the Molecular Targeting and Therapeutics Laboratory at the Sunnybrook Research Institute (SRI), and the SRI Research Chair in Biomolecular Engineering. Dr. Gariépy has had a long standing interest in developing new technologies in the field of biotherapeutics, being cited as an inventor or co-inventor on multiple granted patents and on more than 20 patent applications. He co-founded and was a director [2000-2008] and CSO [2000-2009] of Molecular Templates, Inc. (MTI; MTEM; www.moleculartemplates.com; Austin, Texas), a well-funded, NASDAQ-listed company that focuses on the development of protein-based biotherapeutics (Engineered Toxin Bodies) in the area of Oncology. Dr. Gariépy more recently switched his research focus towards the development of biological therapeutics directed towards combatting cancer and inflammation. His interest in immunotherapy is exemplified by his most recent start-up venture, D5Pharma, where he is the co-founder, CSO, and director.  

Dr. Amanda Sparkes

Amanda obtained her BSc from Memorial University of Newfoundland, a MSc in Biomolecular Sciences and a PhD in Bio-engineering (immunology) from Vrije Universiteit Brussel. Amanda joined the Gariepy lab in 2017 as a Post-Doc where she has developed a research program centered around the design, construction and pre-clinical assesement of immunomodulatory protein therapeutics. 

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Esther Matus

Esther completed her BSc In Biochemistry at the University of Guelph and started her graduate studies in the lab in 2019. As a PhD student in the Medical Biophysics department, she is currently focused on designing and characterizing immunomodulatory bispecific proteins.

Shrayasee Saha

Shrayasee completed her BSc. in Biochemistry at McMaster University. She started in the lab as a summer student in 2018 and is currently a 2nd year MSc. student. Her research focuses on the development of COMP fusion proteins for immunotherapy. 

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Recent Alumni

  • Dr. Peter Lee (Lab Manager/Research Associate)

  • Dr. Mays Alwash (PhD. Student)

  • Dr. Ann Fernando (PhD. Student)

  • Dr. Yu-Heng Vivian Ma (Postdoctoral Fellow)

  • Dr. Nicholas Fischer (PhD. Student)

  • Dr. Aaron Prodeus (PhD. Student/Postdoctoral Fellow)

  • Dr. Aws Abdul-Wahid (Research Associate)

  • Dr. Marzena Cydzik (Research Associate) 

Last updated on Nov-19-2021