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Publications

Perform an automatic Pubmed search to view all of Jean Gariépy's publications.

A selected list of recent publications:


  • Beatty PL, Narayanan S, Gariépy J, Ranganathan S, Finn OJ. (2010) Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer. Cancer Prev Res (Phila Pa). 3(4):438-46.

  • Orava EW, Cicmil N, Gariépy J. Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals. Biochim Biophys Acta. 2010 Feb 6. [Epub ahead of print]

  • Cheung MC, Revers L, Perampalam S, Wei X, Kiarash R, Green DE, Abdul-Wahid A, Gariepy J. An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo. Mol Cancer. 2010 Feb 3;9:28

  • Hassane FS, Ivanova GD, Bolewska-Pedyczak E, Abes R, Arzumanov AA, Gait MJ, Lebleu B, Gariépy J. A Peptide-Based Dendrimer That Enhances the Splice-Redirecting Activity of PNA Conjugates in Cells. Bioconjug Chem. 20(8):1523-1530.

  • Ryan SO, Vlad AM, Islam K, Gariépy J, Finn OJ. Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice. Biol Chem. 2009 390(7):611-8.

  • Ferreira CS, Cheung MC, Bisland S, Missailidis S, Gariepy J. (2009). Phototoxic aptamers selectively enter and kill epithelial cancer cells. Nucleic Acids Res. 37(3):866-76.

  • McCluskey AJ, Poon GMK, Bolewska-Pedyczak E, Srikumar T, Jeram, SM, Raught B, Gariépy J. (2008). The catalytic subunit of shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain. J Mol Biol. 378(2):375-86. 

  • Ferreira CS, Papamichael K, Guilbault G, Schwarzacher T, Missailidis S, Gariepy J. (2008). DNA aptamers against the MUC1 tumour marker: design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumours. Anal Bioanal Chem. 390(4):1039-50.

  • McCluskey AJ, Poon GMK, Gariépy J. (2007). A rapid and universal tandem-purification strategy for recombinant proteins. Protein Sci. 16(12):2726-2732

  • Poon GM, Brokx RD, Sung M, Gariépy J. (2007). Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability. J.Mol Biol. 365(4):1217-31.

  • Poon GM, Gariépy J. (2007). Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells. Biochem Soc Trans. 35(Pt 4):788-93.

  • Tang Y, Yang S, Gariépy J, Scollard DA. and Reilly RM. (2007). Construction and evaluation of the tumor imaging properties of 123I-labeled recombinant and enzymatically generated Fab fragments of the TAG-72 monoclonal antibody CC49. Bioconjug Chem 18(3);677-84.

  • Sung M, Poon GM and Gariépy J. (2006). The importance of valency in enhancing the import and cell routing potential of protein transduction domain-containing molecules. Biochim Biophys Acta 1758(3);355-63.

  • Kawamaura KS, Sung M, Bolewska-Pedyczak E and Gariépy J. (2006). Probing the impact of valency on the routing of arginine-rich peptides into eukaryotic cells. Biochemistry 45(4);1116-27.

  • LaPointe P, Wei X and Gariépy J. (2005). A role for the protease-sensitive loop region of Shiga-like toxin 1 in the retrotranslocation of its A1 domain from the endoplasmic reticulum lumen. J Biol Chem 280(24);23310-8.

  • Brokx R and Gariépy J. (2004). Peptide- and polymer-based gene delivery vehicles. Methods Mol Med 90;139-60.

  • Brokx RD, Revers L, Zhang Q, Yang S, Mal TK, Ikura M and Gariépy J. (2003). Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat. Biochemistry. 42(47);13817-25.

  • Wang J, Reilly RM, Chen P, Yang S, Bray MR, Gariépy J, Chan C, Sandhu J. (2002). Fusion of the CH1 domain of IgG1 to epidermal growth factor (EGF) prolongs its retention in the blood but does not increase tumor uptake. Cancer Biother Radiopharm. 17(6);665-71.

  • Brokx RD, Bolewska-Pedyczak E and Gariépy J. (2003). A stable human p53 heterotetramer based on constructive charge interactions within the tetramerization domain. J Biol Chem. 278(4);2327-32.

  • Kawamura KS, Su RC, Nguyen LT, Elford AR, Ohashi PS and Gariépy J. (2002). In vivo generation of cytotoxic T cells from epitopes displayed on peptide-based delivery vehicles. J Immunol 168(11);5709-15.

  • Gariépy J, Remy S, Zhang X, Ballinger JR, Bolewska-Pedyczak E, Rauth M and Bisland SK. (2002).A simple two-step approach for introducing a protected diaminedithiol chelator during solid-phase assembly of peptides. Bioconjug Chem 13(3);679-84.

 

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